Biotrial
Expertise Partner
Biotrial is a scientifically oriented clinical research organization with 35+ years of experience managing preclinical and clinical CNS studies. The company is comprised of a global team of 350+ employees and physical locations in the US, EU, UK, and Canada. Fully in-house, Biotrial offers In-vivo safety & pharmacology, Patient Clinical trials support and Phase I facilities, as well as Core Lab, Biometrics, and Bioanalytical services for biotech and pharma companies. Biotrial expertise in CNS biomarkers -- EEG & qEEG assessments, ERP, PSG, sleep studies, video-oculography, and various cognitive tests is especially strong.
Neurolief
Expertise Partner
Neurolief is a neuromodulation company dedicated to bringing relief to patients suffering from mental health and neurological disorders. The company consists of highly experienced professionals with a proven track record in neuroscience, neuromodulation technology, and the neurotech industry. Neurolief has developed a disruptive platform technology, the world's first and only non-invasive, multi-channel brain neuromodulation system designed to concurrently neuromodulate major neural pathways in the head and thereby affect brain regions involved in the control and modulation of mood and pain. Neurolief's technology is currently approved by the FDA and CE for the treatment of migraine, and the company is presently seeking regulatory approvals for the treatment of Resistant Major Depression.
Centre for Human Drug Research (CHDR)
Program Partner
The Centre for Human Drug Research (CHDR) is an independent institute that specialises in cutting-edge early-stage clinical drug research. Combining innovative methods and technologies, state-of-the-art facilities, and talented, motivated researchers helps CHDR maximise their clients’ success. In addition, CHDR places the highest priority on their subjects’ comfort and safety, and they play an active role in helping educate the medical and clinical research communities.
bit.bio
Innovation Partner
bit.bio is a synthetic biology company focused on human cells that is advancing medicine and enabling curative treatments. bit.bio’s opti-ox™ precision cell programming technology enables conversion of induced pluripotent stem cells (iPSCs) into any desired human cell type in a single step, at industrial scale, while maintaining exceptional purity and consistency. The ioCells™ research cell product portfolio is opening up new possibilities for studying human biology and developing new medicines in research and drug discovery.
Eurofins BioPharma Product Testing
Innovation Partner
Eurofins BioPharma Product Testing (BPT) delivers a broad range of harmonized methodologies under GMP authorization and certification. We offer R&D services for method development of analytical methods suitable for GMP Chemistry and Microbiology testing and certification of raw materials and finished products. Our 30,000 ft2 laboratory is equipped with state of the art analytical instrumentation and includes a sterility suite, a wide array of stability chambers as well as an extensive controlled drug substance license and narcotics vault.
Ulysses Neuroscience
Innovation Partner
At Ulysses Neuroscience, we stand at the forefront of innovation as your vanguard CRO and translational partner, dedicated to advancing the understanding and treatment of brain disorders. We are committed to accelerating drug discovery programmes of pharmaceutical companies in psychedelics and neuropsychiatric, neurodegenerative, and rare neurodevelopmental disorders by offering cutting-edge clinical and preclinical research services located at Cherrywood Business Park and Trinity College Dublin in the Republic of Ireland. Our research platforms include therapeutic interventions, access to rare diseased populations, extensive clinical and preclinical molecular biomarker capabilities, in vitro human iPSC rodent and rodent assays, preclinical pharmacological and transgenic rodent models coupled with behavioural and EEG analyses. Guided by our core values of patient-centricity, social responsibility, and a focus on translational research, we are your trusted ally in transforming scientific breakthroughs into tangible treatments.
Transpharmation
Exhibition Partner
Transpharmation is a contract research organization led by scientists. Recognized by drug developers worldwide for researching and delivering life-changing medicines, science will always remain our passion. We specialize in cross-species and cross-therapeutic areas in translational pharmacology with AAALAC accreditation.
Our breadth of neuroscience expertise means clients are able to benchmark their compounds against clinical gold standards in well validated behavioural and molecular assays and includes PK & non-GLP safety, Pain, Epilepsy, Depression & Anxiety, EEG, Aging, Neurodegenerative Disorders, Biomarkers, Cognitive Disorders and more.
Clexio Biosciences
Industry Partner
Clexio Biosciences is a clinical-stage company developing novel drugs based on validated MOAs in psychiatric and neurological conditions. We are advancing a pipeline of clinical and preclinical programs, including CLE-100 (NMDA receptor antagonist) currently in Phase 2 for MDD, CLE-400 (alpha-2 adrenergic agonist) currently in Phase 2 for Neuropathic Itch conditions and CLE-905 (M1/M4 agonist) for Schizophrenia currently in IND-enabling studies.
Sama Therapeutics
Event Partner
Sama Therapeutics is a precision neuropsychiatry AI/ML platform that synthesizes and validates predictive biomarkers grounded in neural, physiological, multi-omics, natural language, and behavioral phenotypes. The company's agile SaaS platform, iMAGiNE™, analyzes the transdiagnostic efficacy of pharmaceutical and neurostimulation modalities through precision clinical trials, causal inference, preclinical translation, and generative AI trained on proprietary and open-science datasets. With an extraordinarily interdisciplinary team, Sama Therapeutics is advancing "software as medical device" for a range of indications, including cognitive, affective, interoceptive, and substance use disorders. We invite partners to join our mission unlocking brain health through integrative neurotechnology and proven “transprognostic” algorithms.
SynapCell
Event Partner
SynapCell is a leader in preclinical efficacy testing in CNS disorders, supporting international biopharmaceutical companies in identifying their most promising candidates. The translational, objective EEG endpoints we have characterize in translational animal models in vivo have enabled our clients to unlock the true potential of their drugs. Our areas of expertise span from epilepsy to neuropsychiatry and movement disorders. We strongly believe that regular back-and-forth interactions with Sponsor throughout the project is the key to make the most out of an experiment and deliver clear, comprehensive information to help our clients decide on a GO/NO GO decision towards the clinic.
Advanced Brain Monitoring
Event Partner
Advanced Brain Monitoring is a pioneer in brain health. ABM provided comprehensive EEG services for over 50 clinical trials and research projects where we acquired and curated an expansive EEG database, developed proprietary algorithms and validated unique biomarkers associated with cognitive decline in diseases such as MCI, Alzheimer’s, Lewy Body, Parkinson’s, and psychiatric diseases such as depression and anxiety.
ABM’s platform, including our FDA-cleared, mobile, wireless EEG/ECG device, provides objective, quantitative profiles of neural activity during resting state, attention, memory and sensory tasks. EEG endpoints can be quantified in reference to our normative data or in comparison to patients with neurological and psychiatric disorders.
ABM provides technology and know-how for all phases of clinical trials worldwide. Our team can assist sponsors in translational efforts including identification of EEG biomarkers of target engagement and selecting and optimizing doses. Our large reference datasets offer the potential for adding age and sex matched healthy controls to any clinical trial.
www.advancedbrainmonitoring.com/services/clinical-trials
