Roundtable Discussion: Interpreting Insomnia Signals as a Sleep Biomarker Across Mood Disorders

  •  Differentiating insomnia subtypes (difficulty initiating vs. maintaining sleep vs. early awakening) and their relevance as biomarkers across depression and anxiety
  • How insomnia signatures may stratify patients, predict symptom trajectories, or serve as endpoints across mood disorder trials
  • Opportunities and pitfalls when using sleep related EEG and behavioral signals to map emotional blunting, anhedonia, and anxiety phenotypes
  • Integrating clinical, sponsor, academic, and technology vendor perspectives to advance insomnia as a validated, scalable biomarker