Roundtable Discussion: Clinical Trial Design for Neuropsychiatry: Driving Efficient Early Development & Decision Making

• How can clinical trial designs be adapted to address the complexity and heterogeneity of neuropsychiatric disorders?
• Strategies for selecting endpoints, patient populations, and enrichment approaches that maximize the likelihood of detecting meaningful clinical signals
• Balancing speed, cost, and scientific rigor when designing early-phase neuropsychiatry studies with limited resources
• Lessons learned from recent neuropsychiatric programs on improving recruitment, reducing trial burden, and generating actionable data
• Opportunities to leverage translational insights, biomarkers, and innovative study designs to de-risk development and accelerate progression into later-stage trials

Speakers: