Decoding EEG Biomarkers with Biophysical Models: A New Evidence Layer for Neuropsychiatric Drug Development
- Explaining how biophysically grounded neural models link EEG signals to underlying cell- and circuit-level mechanisms in health and neuropsychiatric disease
- Demonstrating how commonly used EEG biomarkers can be mechanistically interpreted to assess whether neurotherapeutics are acting on intended brain circuits
- Showing how EEG-based circuit modeling can build earlier, translational evidence of target engagement and dosing before human clinical trials
- Outlining the path from academic tool to pharma-facing platform, including spin-out efforts to support R&D decision-making and future treatment response prediction