Decoding EEG Biomarkers with Biophysical Models: A New Evidence Layer for Neuropsychiatric Drug Development

  • Explaining how biophysically grounded neural models link EEG signals to underlying cell‑ and circuit‑level mechanisms in health and neuropsychiatric disease
  • Demonstrating how commonly used EEG biomarkers can be mechanistically interpreted to assess whether neurotherapeutics are acting on intended brain circuits
  • Showing how EEG‑based circuit modeling can build earlier, translational evidence of target engagement and dosing before human clinical trials