Xiohai Wang
Company: Merck
Job title: Director, Neuroscience
Seminars:
Live Q&A 1:20 pm
day: Day One
Translational Pharmacology & Biomarker Development of the Novel α7 nAChR Positive Allosteric Modulator BNC375 12:15 pm
• α7 positive allosteric modulators (PAMs) exhibit superior efficacy and selectivity to α7 agonists • BNC375 improves cognitive function in aged African green monkeys which manifest pathological and cognitive hallmarks of Alzheimer’s disease • BNC375 enhances 13C enrichment in brain metabolites in rat and nonhuman primate cortex following 13C glucose infusion, a novel translation biomarker…Read more
day: Day One