Xiohai Wang

Xiohai Wang

Company: Merck

Job title: Director, Neuroscience

Seminars:

Live Q&A 1:20 pm

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day: Day One

Translational Pharmacology & Biomarker Development of the Novel α7 nAChR Positive Allosteric Modulator BNC375 12:15 pm

• α7 positive allosteric modulators (PAMs) exhibit superior efficacy and selectivity to α7 agonists • BNC375 improves cognitive function in aged African green monkeys which manifest pathological and cognitive hallmarks of Alzheimer’s disease • BNC375 enhances 13C enrichment in brain metabolites in rat and nonhuman primate cortex following 13C glucose infusion, a novel translation biomarker…Read more

day: Day One

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