Psychedelics 2.0 – Novel preclinical approaches to investigate mechanisms of action and efficacy of glutamatergic and serotonergic psychedelics

Time: 9:15 am
day: Day One


  • Acute and long-term behavioural and molecular efficacy of ketamine in the rat IFN-alpha model of depression
  • Exploring changes in synaptic markers (BDNF; pre-synaptic SV2A and synaptophysin; post-synaptic PSD-95 and spinophilin) induced by psychedelics
  • Using established and innovative behavioural endpoints to understand psychedelic effects on brain function
  • Preclinical electrophysiology as a translational biomarker of acute and long-term effects of psychedelics on brain activity